2-Pyrrolidone

1. Product Overview

2-Pyrrolidone is a high-purity, polar aprotic solvent and chemical intermediate derived from gamma-butyrolactone (GBL) and ammonia. It is primarily used in the production of pharmaceuticals, agrochemicals, and advanced polymers, as well as in specialty solvent applications. The key value proposition is its exceptional solvency power, thermal stability, and low volatility, enabling higher reaction yields and purer end products. Strategically, 2-Pyrrolidone is critical for manufacturers seeking to replace restricted solvents (e.g., NMP, DMF) while maintaining process efficiency, positioning it as a future-proof raw material in regulated markets.

2. Key Specifications & Technical Characteristics

• Chemical composition: 2-Pyrrolidone (CAS 616-45-5), C₄H₇NO, ≥99.5% purity

• Grade: Industrial grade / Pharmaceutical intermediate grade available

• Physical form: Clear, colorless to pale yellow liquid

• Melting point: 24–25°C (solidifies below 24°C, handle with mild heating)

• Boiling point: 245°C

• Density: ~1.116 g/cm³ at 20°C

• Water content: ≤0.2% (Karl Fischer)

• Ash content: ≤0.05%

• Packaging options: 200 kg net HDPE drums, 1,000 kg IBC totes, bulk ISO tanks

• Shelf life: 24 months when stored in sealed, dry, cool conditions (avoid moisture and strong oxidizers)

3. Core Industrial Applications

• Pharmaceuticals: Synthesis of pyrrolidone-based APIs, including nootropics (e.g., piracetam) and antivirals. Outperforms DMF in reaction kinetics due to higher polarity and lower toxicity profile.

• Agrochemicals: Production of fungicides, herbicides, and plant growth regulators. Enables higher yield in amidation and substitution reactions compared to traditional ether solvents.

• Polymer industry: Processing of high-performance polyamides, polyurethanes, and engineering plastics. Provides superior wetting and leveling properties for coatings and electronic materials.

• Electronics & industrial cleaning: Stripping photoresists and cleaning precision components without residue, offering lower corrosion risk than chlorinated solvents.

• Cost advantage: Reduces downstream purification steps, cutting overall production cost by 8–12% in validated processes.

4. Competitive Advantages

• Quality consistency: Batch-to-batch purity variance <0.1% via SPC-controlled synthesis; ISO 9001:2025 certified manufacturing.

• Supply reliability: Dedicated production lines with 12,000 MT annual capacity; safety stock held in three regional hubs (Asia, Europe, NA).

• Logistics capability: Temperature-controlled bulk liquid logistics network; 48-hour dispatch for urgent orders.

• Price competitiveness: Direct from manufacturer — eliminates 2–3 intermediary markups; long-term fixed-price contracts available.

• Sustainability: Fully REACH and TSCA compliant; 98% recoverable by distillation; zero hazardous waste discharge in production.

• Technical support: Full SDS, CoA, stability study reports, and application lab support for formulation optimization.

5. Commercial & Supply Information

• Minimum order quantity (MOQ): 20 MT (bulk)

• Loading capacity: 20–22 MT per 20-ft ISO tank container; 80 drums (16 MT) per 20-ft general purpose container

• Lead time: 15 days ex-works for bulk; 7 days for drummed stock

• Incoterms supported: FOB, CIF, EXW (negotiable)

• Payment terms: LC at sight, TT advance (for first order), or net 30 days for approved accounts

For pricing, samples, or technical datasheet, request a strategic sourcing quote.