• Worldwide Delivery Mon-Sat 7:00AM - 21:00PM
'

Mandelic Acid

Mandelic Acid
Mandelic Acid - Image 2
Mandelic Acid - Image 3
Mandelic Acid - Image 4
Mandelic Acid - Image 5
Mandelic Acid - Image 6
Mandelic Acid - Image 7
Mandelic Acid - Image 8
Mandelic Acid - Image 9

Mandelic Acid

£2,000.00

High-purity Mandelic Acid (CAS 90-64-6) available in pharmaceutical, cosmetic, and technical grades, supplied in standardized packaging from 25 kg to full IBC totes with full chain-of-custody documentation.

Competitive Advantage Spotlight
Consistent >99.5% purity verified by ISO 17025-accredited third-party labs, competitively priced through vertically integrated production, and backed by just-in-time logistics across North America, Europe, and APAC.

Category:

Description

1. Product Overview
Mandelic Acid is an alpha-hydroxy acid (AHA) distinguished by its larger molecular weight and aromatic ring structure, offering superior lipophilicity and lower irritancy compared to glycolic or lactic acid. Its primary industrial use is as a high-performance intermediate in specialty chemical synthesis, advanced pharmaceutical formulations (antibiotics, urinary antiseptics), and precision polymer manufacturing. The key value proposition is its dual functionality: effective exfoliation and antibacterial activity combined with exceptional thermal stability, enabling formulators to achieve targeted results without aggressive side effects. Strategically, it is critical for suppliers moving toward “mild yet potent” chemical actives in regulated markets like North America and Europe.

2. Key Specifications & Technical Characteristics

  • Chemical composition: C₈H₈O₃ (2-Hydroxy-2-phenylacetic acid); ≥99.0% purity (pharma grade available)

  • Physical form: White to off-white crystalline powder

  • Particle size: 80–200 mesh (standard); micronized available upon request

  • Melting point: 119–121°C

  • Bulk density: 0.55–0.65 g/cm³

  • Solubility: Soluble in water (15 g/100 mL at 25°C), freely soluble in ethanol, propylene glycol, and ethyl acetate

  • Heavy metals: ≤10 ppm (Ph.Eur./USP compliant)

  • Packaging options: 25 kg multi-layer kraft paper bags with PE liner; 500 kg FIBC bulk bags; 200 kg HDPE drums

  • Shelf life: 24 months in original unopened packaging, stored below 30°C in dry, ventilated area

3. Core Industrial Applications

  • Pharmaceutical synthesis: Used as a key intermediate in the production of cyclandelate (vasodilator) and mandelamine (methenamine mandelate—urinary tract antiseptic). Outperforms benzoic acid derivatives due to superior hydrolytic stability and lower skin penetration risk.

  • Cosmeceutical & personal care: Base active in chemical peels (10–25% concentrations), acne serums, and anti-aging formulations. Its larger molecular weight reduces dermal irritation vs. glycolic acid, allowing higher concentration usage in professional products without neutralization complexity.

  • Industrial polymer additives: Acts as a chain terminator in phenolic resin manufacturing and as a corrosion inhibitor in metalworking fluids. Provides 30% longer bath life compared to citric acid in aqueous systems due to lower metal chelation interference.

  • Fine chemical synthesis: Preferred chiral building block for enantioselective reactions where mandelate esters are required—offers higher yield consistency (95%+ vs. 85% for racemic alternatives) in asymmetric hydrogenation.

4. Competitive Advantages

  • Quality consistency: ISO 9001:2025 certified production with batch-to-batch HPLC analysis (RSD <1.5%); each shipment includes COA, MSDS, and residual solvent report.

  • Supply reliability: Dual-source manufacturing (Asia & Europe) with safety stock of 200 MT held in Rotterdam and Houston hubs; 98.7% on-time-in-full performance over 24 months.

  • Logistics capability: Temperature-controlled dry container shipping; hazardous class not required (non-UN2800); compliant with REACH, FDA 21 CFR, and China GB standards.

  • Price competitiveness: Direct-from-crystallization supply chain eliminates intermediate brokers—landed cost 12–18% below EU spot averages on FOB/CIF terms.

  • Sustainability: Solvent recovery rate >92% in production; available with carbon-neutral shipping via verified emission offsets.

  • Technical support: Dedicated application lab with 48-hour response for formulation compatibility testing and impurity troubleshooting.

5. Commercial & Supply Information

  • Minimum Order Quantity (MOQ): 1 MT (trial order); 5 MT (standard contract)

  • BULK 20MT Loading Capacity: 20 MT per 20’ dry container (960 bags of 25 kg or 40 FIBCs of 500 kg)

Additional information

Benefits

Exfoliation: Mandelic acid can help with exfoliation, hydration, and firmness.
Acne: Mandelic acid has been studied for its use with acne.
Sensitive skin: Mandelic acid is sometimes considered a gentle AHA, so it may be suitable for people with sensitive skin.
How Does it Work

Mandelic Acid 40% Topical Liquid is a specially crafted formulation that is applied directly to the skin to exert its therapeutic effects. Mandelic acid, an alpha hydroxy acid (AHA) derived from bitter almonds, works primarily by accelerating cell turnover. When applied to the skin, it gently exfoliates the uppermost layer of the epidermis, removing dead skin cells and promoting the emergence of new, healthy skin cells. This process of exfoliation can help to unclog pores, reduce the appearance of fine lines, and improve skin texture and tone.

The mechanism of action of mandelic acid involves breaking the bonds that hold dead skin cells together on the skin's surface. This action not only facilitates exfoliation but also enhances the skin's absorption of other skincare products. By promoting the shedding of the outer skin layer, mandelic acid can also help to fade hyperpigmentation, such as age spots, melasma, and scars, leading to a more even skin tone. Its larger molecular size compared to other AHAs allows for a slower, more even penetration, which can reduce the risk of irritation, making it suitable for sensitive skin types and those new to acid exfoliation.

Additionally, mandelic acid possesses antibacterial properties, making it effective in treating acne-prone skin. It can help to reduce inflammation and bacterial growth associated with acne, and its exfoliating action helps to prevent the formation of new comedones (blackheads and whiteheads). Furthermore, mandelic acid has been found to have some benefit in treating photoaging due to its ability to stimulate collagen production, thereby improving skin elasticity and reducing the appearance of wrinkles.

For patients with rosacea or other inflammatory skin conditions, mandelic acid can provide benefits due to its anti-inflammatory properties. It can help to soothe the skin and reduce redness without causing the irritation that can sometimes result from the use of other AHAs. The formulation's 40% concentration allows for potent therapeutic action, yet it should be used with caution, and sun protection is advised due to the increased sensitivity to UV radiation that can result from exfoliating treatments.

It is important for both patients and prescribers to understand that while mandelic acid can provide significant benefits for various skin conditions, it should be used as part of a comprehensive skin care regimen. It is also essential to introduce mandelic acid gradually into a skincare routine to allow the skin to adapt and to minimize potential irritation. As with any topical treatment, individual responses can vary, and it may take several weeks to observe noticeable improvements in skin condition.

If you have any questions about the Mandelic Acid 40% Topical Liquid formulation or its suitability for a particular skin condition, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this product.
Drug Interactions

Mandelic Acid 40% Topical Liquid is a formulation intended for direct application to the skin. Mandelic acid is an alpha hydroxy acid (AHA) that is commonly used for its exfoliating properties, which can help in the treatment of various skin conditions such as acne, melasma, age spots, and wrinkles. It accelerates cell turnover by dissolving the tiny bonds that hold skin cells together, helping to remove dead skin on the surface that can lead to dull complexions and fine lines.

When using Mandelic Acid 40% Topical Liquid, it is important to consider potential drug interactions, particularly with other topical agents. Concurrent use of other exfoliants, such as other AHAs (glycolic, lactic acid), beta hydroxy acids (salicylic acid), or retinoids (tretinoin, adapalene) can increase the risk of skin irritation, redness, and peeling. It is generally recommended to avoid using multiple exfoliating agents together unless directed by a healthcare provider.

Additionally, products containing benzoyl peroxide should be used with caution, as they may cause a temporary staining of the skin when used with mandelic acid. Sun sensitivity may be increased when using mandelic acid, so it is crucial to apply sunscreen and limit sun exposure while using this product and for a week afterwards. This is because AHAs can make the skin more susceptible to UV damage due to their exfoliating action on the skin's surface.

Patients should also be aware that the use of mandelic acid with topical anesthetics or corticosteroids could potentially increase the absorption of these agents, leading to increased systemic exposure and potential side effects. It is advisable to consult with a healthcare provider before combining such treatments.

It is important to note that while mandelic acid is used topically and is not known to have significant interactions with oral medications, patients should always inform their healthcare provider of all the medications and products they are using, including over-the-counter drugs, herbal supplements, and cosmeceuticals. This will help to ensure safe and effective use of the Mandelic Acid 40% Topical Liquid.

For any questions or concerns regarding the use of Mandelic Acid 40% Topical Liquid or potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide guidance and support to ensure the safe and effective use of this formulation for both patients and prescribers.
How to use

After cleansing and hydrating, apply a thin layer of mandelic acid to affected areas.
Follow with serums and moisturizer.
Apply SPF as the last step in your morning skincare routine.
Key ingredients

Mandelic Acid, Sodium Hyaluronate Crosspolymer, Tasmannia Lanceolata Fruit/Leaf Extract
Other uses

Mandelic acid is also a useful precursor to various drugs.
It has antibacterial properties.
It's a human xenobiotic metabolite.
Precautions

Do a patch test before using.
Discontinue use if irritation occurs.
Avoid contact with eyes.
If irritation persists, discontinue use and consult a physician.
Related AHAs

Other types of AHAs found in skincare lines include glycolic acid and citric acid.

Reviews

There are no reviews yet.

Be the first to review “Mandelic Acid”

Your email address will not be published. Required fields are marked *

Related products

chemicalsuppliesmktplc

Welcome to Chemical Supplies Marketplace, the premier destination for sourcing high-quality chemicals for individuals, businesses, and heavy industries around the globe.

IMPORTANT PAGES

Get In Touch

Chemical Supplies Marketplace

Tel: +447986954139

Email: info@chemicalsuppliesmktplc.co.uk

Address: 209-210 Bollo Lane, London W3 8QU

Open Mon – Fri / 7:00am – 21:00pm

©2025, All Rights Reserved by Chemical Supplies Marketplace

Add to cart