Mannitol

Description

1. Product Overview
   Mannitol is a high-purity sugar alcohol (polyol) with the chemical formula C₆H₁₄O₆ (CAS 69-65-8, E421), produced industrially via catalytic hydrogenation of fructose. Its primary industrial use spans pharmaceutical excipients, food sweeteners, and chemical synthesis, where it serves as a tablet diluent, bulking agent, osmotic diuretic, and anti-caking additive. The key value proposition lies in its exceptional stability, low hygroscopicity, non-GMO/allergen-free profile, and sweet taste without significant calorie absorption. Strategically, mannitol is critical amid the 2026 global supply shortage, making reliable sourcing essential for uninterrupted pharmaceutical and food production.

2. Key Specifications & Technical Characteristics

• Chemical composition: D-Mannitol (sugar alcohol), C₆H₁₄O₆, CAS 69-65-8, E-number E421

• Purity level/grade: Pharmaceutical-grade (USP/EP/BP compendial), food-grade (E421), high-purity low-endotoxin/low-metals (HPLE-LM) for biopharmaceuticals

• Physical characteristics: White crystalline powder or granules; sweet taste; excellent water solubility; low hygroscopicity; particle size suitable for tablet compression

• Packaging options: Industrial bulk bags (25kg, 500kg, 1MT), pharmaceutical-grade sealed containers, custom packaging per buyer requirements

• Shelf life: 2–3 years under proper storage (dry, <25°C); stable due to low moisture absorption

3. Core Industrial Applications

   Primary Industry	Specific Operational Use Case	Competitive Performance Advantage
   Pharmaceutical	Tablet/capsule diluent, bulking agent, excipient in chewable tablets; osmotic diuretic for cerebral edema, renal failure prophylaxis	Meets non-negotiable USP/EP/BP pharmacopeial standards; lowest endotoxin/metals for therapeutic formulations
   Food & Beverage	Sugar-free/low-calorie sweetener, anti-caking agent, texturizer in diabetic foods	Poor intestinal absorption = low-calorie; stable in processing; allergen-free/non-GMO
   Industrial/Chemical	Fermentation substrate, chemical synthesis intermediate, personal care product base	Excellent stability enables durable formulations; cost-effective vs. alternative polyols

4. Competitive Advantages

• Quality consistency: Batch-to-batch HPLE-LM™ purity assurance under full cGMP; stringent impurity profiles for food/pharma

• Supply reliability: Proven track record during 2026 shortage; stable production capacity with strong manufacturer relationships

• Logistics capability: Global shipping with flexible packaging (25kg–1MT); optimized lead times

• Price competitiveness: Cost-effective vs. alternatives due to efficient fructose hydrogenation process

• Sustainability: Naturally derived from fruits/vegetables/sugar cane; non-GMO, allergen-free, environmentally benign

• Technical support: Full regulatory documentation (USP/EP/BP, E421 compliance); cGMP certification available

5. Commercial & Supply Information

• Minimum order quantity (MOQ): BULK 20MT