Cyanocobalamin (B12)

Description

1. Product OverviewCyanocobalamin (Vitamin B12) is a high-purity, crystalline cobamide compound widely recognized as the most stable and bioavailable form of vitamin B12 for industrial applications. Its primary industrial use is as a critical nutritional supplement in pharmaceuticals, animal feed, and dietary supplement manufacturing, where it supports hematopoietic function and prevents B12 deficiency. The key value proposition lies in its USP/Ph. Eur.-grade purity (96–102%), ensuring consistent bioactivity and regulatory compliance across global markets. Strategically, it is indispensable in sectors facing rising B12 deficiency rates and growing demand for fortified nutrition, making it a cornerstone sourcing item for enterprise suppliers.

2. Key Specifications & Technical Characteristics

• Chemical composition: C₆₃H₈₈CoN₁₄O₁₄P (α-(5,6-Dimethylbenzimidazolyl)cyanocobamide)

• CAS Number: 68-19-9

• Molecular Weight: 1355.37 g/mol

• Purity/Grade: 96.0% – 102.0% (on dried basis), USP/Ph. Eur./BP compliant

• Physical form: Dark red crystalline powder or crystals

• Color: Dark red

• Odor: Odourless

• Bulk density: 450–600 kg/m³

• Solubility: 12 g/L in water; soluble in ethanol (~750 g/L)

• pH: 6.0 (20°C, 1 g/L in H₂O)

• Melting point: >300°C

• Packaging options: Sealed foil bags, amber glass bottles, or 25 kg drum containers (light-protected)

• Shelf life: 2–3 years when stored at 15–25°C, protected from light

3. Core Industrial Applications

• Primary industries:

  • Pharmaceutical manufacturing (injectables, oral formulations)

  • Dietary supplement and nutraceutical production

  • Animal feed and livestock nutrition (especially poultry, dairy, and swine)

• Specific operational use cases:

  • Treatment and prevention of vitamin B12 deficiency (e.g., pernicious anemia)

  • Fortification of fortified foods and liquid/solid dietary supplements

  • Hematopoietic support in veterinary feed to improve growth rates and red blood cell formation

• Performance advantages over alternatives:

  • Higher stability than hydroxocobalamin in aqueous formulations

  • Superior bioavailability and longer shelf life due to cyanide ligand protection

  • Cost-efficient per unit of bioactive B12 compared to plant-derived alternatives

4. Competitive Advantages

• Quality consistency: Certified to USP, Ph. Eur., and BP standards with rigorous spectrophotometric validation (absorbance ratios at 278/361/550 nm)

• Supply reliability: Manufactured in bulk with GMP-compliant facilities; consistent 96–102% assay across batches

• Logistics capability: Light-protected, moisture-resistant packaging enables global shipping; compatible with standard dry-container logistics

• Price competitiveness: Economical bulk pricing for 20MT orders; lower cost-per-mg than biological extraction methods

• Sustainability benefits: Vegetable-origin production (non-animal-derived); low environmental footprint in synthesis

• Technical support: Full documentation (COA, MSDS, regulatory dossiers) and formulation guidance available

5. Commercial & Supply Information

• Minimum Order Quantity (MOQ): BULK 20MT [query]

• Loading capacity: ~18–20 MT per 40’ HC dry container (depending on packaging density)

• Packaging for bulk: 25 kg light-protected drums; 20 MT fits in 1–2 containers [query]