1,4-Dioxane

Description

1. Product Overview

1,4-Dioxane is a high-purity, stable cyclic ether solvent, recognized for its exceptional solvency power in demanding industrial synthesis and processing applications. Its primary industrial use is as a reaction medium and stabilizer in the production of chlorinated solvents, pharmaceuticals, and agricultural chemicals, as well as a processing aid in specialty chemical manufacturing. The key value proposition lies in its unmatched ability to dissolve both polar and non-polar compounds, enabling higher reaction yields and process efficiency. Strategically, securing a reliable supply of high-grade 1,4-Dioxane is critical for manufacturers seeking to maintain batch consistency, reduce production downtime, and meet stringent quality specifications in regulated end-markets.

2. Key Specifications & Technical Characteristics

• Chemical composition: Cyclic dialkyl ether (C₄H₈O₂); CAS No. 123-91-1

• Purity level: ≥99.8% (anhydrous grade); available in technical grade (≥99.0%) and HPLC grade (≥99.9%)

• Physical characteristics:

  • Form: Clear, colorless liquid

  • Odor: Mild, ether-like

  • Density: 1.033 g/cm³ at 25°C

  • Boiling point: 101.1°C

  • Freezing point: 11.8°C

  • Viscosity: 1.2 cP at 25°C

• Packaging options:

  • 200 L steel drums (net 200 kg)

  • 1,000 L IBC totes (net 1,000 kg)

  • Bulk isotanks (20,000–24,000 kg)

  • Custom packaging upon request

• Shelf life: 24 months from date of manufacture when stored in sealed, moisture-free conditions under nitrogen blanket; stabilized grade available

3. Core Industrial Applications

• Primary industries: Pharmaceutical synthesis, agrochemical manufacturing, chlorinated solvent production, specialty polymers, and laboratory reagent supply.

• Specific operational use cases:

  • Reaction solvent for Grignard reactions, alkylations, and polymerizations where aprotic polar media are required.

  • Stabilizer for 1,1,1-trichloroethane in metal cleaning formulations.

  • Process aid in production of triethylene glycol and polyester resins.

• Performance advantage: Compared to THF or diethyl ether, 1,4-Dioxane offers higher thermal stability and broader polarity range, reducing side reactions and improving mass transfer in heterogeneous systems.

• Efficiency/cost advantage: Lower volatility relative to lower ethers reduces solvent loss to evaporation; recyclability via distillation lowers net solvent cost per batch in continuous processes.

4. Competitive Advantages

• Quality consistency: ISO 9001:2025 certified production with SPC-controlled batch release; each shipment includes CoA with trace metals and water content (<0.05%).

• Supply reliability: Multi-continent production footprint (Asia, Europe, Americas) with buffer stock warehousing; 98% on-time-in-full (OTIF) performance over trailing 12 quarters.

• Logistics capability: Dedicated hazmat logistics partner network (UN 1165, Class 3, PG II) enabling door-to-door delivery including cross-border regulatory compliance.

• Price competitiveness: Volume-based tiered pricing (contract, spot, long-term) with fuel and feedstock index-linked adjustment mechanisms.

• Sustainability & compliance: REACH, TSCA, and K-REACH registered; available with low inhibitor (<10 ppm BHT) or inhibitor-free upon request; closed-loop drum return program offered for high-volume accounts.

• Technical support: In-house application chemists provide reaction optimization, solvent recovery protocols, and impurity remediation guidance.

5. Commercial & Supply Information

• Minimum order quantity (MOQ): 20 MT (one full container load) for standard technical grade; 4 MT (20 drums) for HPLC/anhydrous grade

• Bulk loading capacity: 20 MT per 20-ft ISO tank container (maximum net weight) – equivalent to 19,360 liters at 20°C