Niacinamide (B3)

Description

1. Product Overview

Niacinamide (Vitamin B3) is a high-purity industrial-grade amide of nicotinic acid supplied for large-scale manufacturing and formulation applications. Primarily used as an active ingredient, process intermediate, and functional additive across pharmaceutical, nutraceutical, cosmetic, and specialty chemical supply chains, it delivers consistent bioactive performance and formulation stability. Its key value proposition is dependable, pharma-compatibility-grade purity combined with scalable logistics and traceable quality control—enabling manufacturers to reduce batch variation, accelerate time-to-market, and meet regulatory/compliance requirements. Strategically, Niacinamide addresses rising demand for well-documented, high-quality B3 sources as global formulators shift toward standardized ingredients with proven supply continuity.

2. Key Specifications & Technical Characteristics

• Chemical name: Niacinamide (Nicotinamide)

• Chemical formula: C6H6N2OC6​H6​N2​O

• CAS number: 98-92-0

• Grade: Industrial / Pharma-compatible (specify certificate: Certificate of Analysis and optional GMP batch documentation available)

• Purity: Typical ≥ 99.0% w/w (custom grades and tighter spec options available upon request)

• Physical form: Free-flowing crystalline powder

• Color: White to off-white

• Particle size: D50 and D90 options available on request; standard industrial grade D50 ≈ 30–150 µm (custom milling available)

• Bulk density: Typical 0.45–0.65 g/cm³ (tapped density and pouring density measured and provided per batch)

• Solubility: Readily soluble in water; compatible with common cosmetic and aqueous pharmaceutical systems

• Moisture content: ≤ 0.5% w/w (typical, measured by loss on drying)

• Heavy metals: Meets industry thresholds; specific limits supplied on CoA

• Residual solvents: Compliant with applicable regulatory guidance when required (specified on CoA)

• Microbial load: Low bioburden; microbial limits and testing available for pharma-compatible lots

• Packaging options: 25 kg HDPE-lined fiber drums; 500 kg FIBCs; 1 MT sealed intermediate bulk containers (IBCs); custom packaging available for export or regulated supply chains

• Shelf life: 24 months when stored in sealed packaging, in a cool, dry place away from direct sunlight (stability data and retest period provided)

• Storage conditions: Recommended 2–30°C, humidity <60%, avoid prolonged exposure to heat and moisture

3. Core Industrial Applications

• Pharmaceuticals: Active pharmaceutical ingredient (API) precursor, vitamin supplementation formulations, and stabilizer in oral and topical products. Used in tablet and capsule formulations for consistent potency and tight impurity profile.

• Nutraceuticals & Food Ingredients: Fortification in powdered blends, premixes, and beverage concentrates. Delivers measured bioavailability and complies with food-grade handling when required.

• Cosmetics & Personal Care: Functional ingredient for anti-aging, skin-lightening, and barrier-repair formulations (creams, serums, lotions). Provides proven dermal effects with high solubility for aqueous and emulsion systems.

• Specialty Chemicals & Coatings: Additive for process chemistries where amide functionality improves stability or performance; used in certain polymer or resin formulations.

• Industrial R&D & Contract Manufacturing: Reliable intermediate for contract manufacturers requiring traceable documentation and consistent lot-to-lot performance.

Why it outperforms alternatives:

• High and consistent purity reduces downstream variability and rework.

• Controlled particle-size distributions enable reproducible blending, dissolution, and compaction behavior in tableting and topical systems.

• Comprehensive batch documentation (CoA, stability, impurity profile) simplifies regulatory submissions and supplier qualification.

• Multiple packaging and handling configurations reduce conversion costs for high-throughput production lines.

4. Competitive Advantages

• Quality consistency: Rigorous in-house QC and third-party testing ensure batch-to-batch uniformity; CoA provided for each shipment.

• Supply reliability: Secured raw material sourcing and predictable production scheduling support long-term contracts and rush replenishment.

• Logistics capability: Multiple export-grade packaging formats, consolidation hubs, and experience with global container shipping; documentation support (MSDS, customs paperwork) included.

• Price competitiveness: Scalable pricing tiers for contract volumes and long-term supply agreements; competitive CIF/FOB terms available.

• Sustainability: Low-waste manufacturing routes and waste-stream controls; options for green-certified production on request and reporting for scope-relevant emissions where required.

• Technical support: Dedicated technical dossier (spec sheets, handling guides, safety datasheets), formulation support, and sample availability for qualification runs.

• Compliance readiness: Capability to supply pharma-compatible lots with documented testing for heavy metals, residual solvents, and microbial limits to support GMP workflows.

5. Commercial & Supply Information

• Minimum order quantity (MOQ): BULK 20MT

• Loading capacity (MT per container): Typical 20-foot container: up to 20 MT (in 25 kg drums or 500 kg FIBC configurations, subject to packing method and transport regulations); 40-foot container: up to 24–26 MT depending on palletization and packaging. Confirm packing plan during order.

• Lead time: Standard lead time 4–8 weeks for bulk production; expedited options available subject to inventory and shipping schedules.

• Incoterms & pricing: FOB, CIF, and DAP pricing offered; volume discounts for annual contracts and multi-container bookings.

• Documentation provided: Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), SDS, packing list, commercial invoice, and optional GMP/quality audit support.

• Contact & qualification: Samples for testing available on request; vendor qualification packages provided for procurement and regulatory teams.