Polyethylene glycol methyl ether

Description

1. Product Overview
Polyethylene glycol methyl ether (mPEG) is a high-performance, methoxy-capped polyethylene glycol derivative engineered for enhanced chemical stability and reduced reactivity compared to standard PEG. It serves as a critical intermediate in pharmaceutical formulations, surface modifications, and industrial polymer synthesis, where precise control over hydrophilicity and non-fouling properties is required. The key value proposition lies in its ability to impart biocompatibility and steric stabilization while eliminating unwanted side reactions—making it strategically indispensable for advanced drug delivery systems and high-purity industrial coatings.

2. Key Specifications & Technical Characteristics

• Chemical composition: Methoxy poly(ethylene glycol) – CH₃(OCH₂CH₂)nOH with controlled molecular weight distribution

• Purity grade: Industrial grade (≥98%) / Pharmaceutical grade (≥99.5%) available

• Physical form: White to off-white waxy solid or free-flowing powder (depending on molecular weight)

• Molecular weight options: 350, 550, 750, 1000, 2000, 5000 Da (customizable)

• Hydroxyl value: ≤5 mg KOH/g (for pharmaceutical grade)

• Water content: ≤0.5% (Karl Fischer)

• Density (bulk): Approx. 1.08–1.10 g/cm³ at 60°C

• Packaging options: 25 kg fiber drums, 200 kg LDPE-lined drums, 1,000 kg IBC totes

• Shelf life: 24 months in original unopened container (store below 30°C, dry environment)

3. Core Industrial Applications

• Pharmaceutical & Biotech: Used as a precursor for PEGylated proteins, peptides, and small-molecule conjugates. mPEG outperforms diol PEG by eliminating cross-linking side reactions, improving drug half-life and reducing immunogenicity.

• Personal Care & Cosmetics: Acts as a non-ionic surfactant and humectant in creams, lotions, and hair products. Provides superior moisture retention and skin feel compared to glycol ethers, with lower irritation potential.

• Industrial Coatings & Adhesives: Functions as a reactive diluent and leveling agent in waterborne and UV-curable systems. Enables faster cure times and better film uniformity than conventional solvents.

• Water Treatment & Oilfield Chemicals: Used as a foam control agent and lubricity enhancer. Cost advantage over specialty fluorosurfactants with equivalent thermal stability up to 200°C.

4. Competitive Advantages

• Quality consistency: Batch-to-batch variability <2% (measured by GPC and hydroxyl number) – certified via ISO 9001:2025 and cGMP-ready documentation.

• Supply reliability: Dual-sourced raw materials with 6-month safety stock buffer; 99.5% on-time delivery rate over 18 months.

• Logistics capability: Global distribution hubs (Asia, Europe, NA) enabling 7-day lead time to major industrial zones.

• Price competitiveness: 12–18% lower TCO than European or Japanese equivalents due to integrated manufacturing and energy-efficient ethoxylation process.

• Sustainability benefits: 100% phthalate-free, heavy-metal-free, and available with bio-based ethylene oxide (ISCC PLUS certified).

• Technical support: Full SDS, COA, method validation protocols, and formulation troubleshooting from application engineers.

5. Commercial & Supply Information

• Minimum order quantity (MOQ): 500 kg (industrial grade) / 200 kg (pharmaceutical grade)

• BULK 20MT loading capacity: Yes – 20 MT per 20-ft container (packaged in 1,000 kg IBC totes or 25 kg drums on pallets, 20 pallets per container)

• Loading capacity per TEU: 20 metric tons net weight (maximum utilizing 95% volumetric efficiency)