Proteinase K

£80,000.00

Proteinase K is a broad-spectrum, high-activity serine protease engineered for robust performance across DNA/RNA extraction, endotoxin removal, and industrial biocatalysis. It delivers consistent digestion even under extreme conditions (up to 65°C, pH 7.5–12.0, and in the presence of SDS or urea).

Competitive Advantage Spotlight
Superior lot-to-lot consistency with ≥95% residual activity after accelerated stability testing, enabling precise, reproducible results at lower enzyme loading than standard alternatives.

Description

1. Product Overview

Proteinase K is a broad-spectrum serine protease enzyme widely used for the efficient digestion of proteins in complex biological and industrial systems. It is primarily utilized in molecular biology, biotechnology, and pharmaceutical manufacturing to degrade proteins and facilitate nucleic acid extraction and purification. Delivering high enzymatic activity across a wide range of conditions, Proteinase K ensures consistent, reliable performance in critical workflows. Strategically, it is an essential reagent in modern bio-processing and diagnostics, enabling high-throughput, contamination-free results that support precision-driven industries.


2. Key Specifications & Technical Characteristics

  • Chemical Composition: Serine protease enzyme derived from microbial fermentation
  • Purity/Grade: ≥ 30 U/mg activity (customizable higher activity grades available)
  • Physical Form: Lyophilized powder or liquid solution
  • Color: سفید to off-white powder / clear liquid
  • Solubility: Highly soluble in water and standard buffer systems
  • Optimal Conditions: فعال across pH 4–12; optimal activity at ~pH 7.5–12 and 50–65°C
  • Stability: Stable in presence of SDS, urea, and EDTA
  • Packaging Options: 100g, 500g, 1kg, and bulk industrial packaging
  • Shelf Life: 24–36 months under recommended storage conditions (-20°C for long-term stability)

3. Core Industrial Applications

Proteinase K is extensively used in biotechnology, pharmaceuticals, diagnostics, and research laboratories. Its primary application lies in DNA and RNA extraction workflows, where it removes protein contaminants, ensuring high-purity nucleic acid yields. It is also critical in enzyme-based processing, cell lysis, and biopharmaceutical purification systems. Compared to alternative proteases, Proteinase K demonstrates superior stability under denaturing conditions and maintains activity in the presence of detergents and inhibitors, resulting in higher process efficiency, reduced processing time, and improved downstream accuracy.


4. Competitive Advantages

  • High Activity Consistency: لضمان reproducible results across batches
  • Robust Supply Chain: Reliable global sourcing and large-scale production capability
  • Flexible Logistics: Scalable packaging and export-ready handling for bulk buyers
  • Cost Efficiency: Optimized production enabling competitive industrial pricing
  • Operational Stability: Performs under harsh chemical and thermal conditions
  • Sustainability: Produced via controlled microbial fermentation with minimized environmental impact
  • Technical Support: Comprehensive documentation, COA, and application guidance available

5. Commercial & Supply Information

  • Minimum Order Quantity (MOQ): Bulk 20 MT
  • Loading Capacity: 20–22 MT per 20-ft container depending on packaging configuration

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