Cyclopropylamine

1. Product Overview

Cyclopropylamine is a high-purity, cyclic aliphatic amine recognized for its unique three-membered ring structure, enabling superior reactivity and stability in complex organic syntheses. It is primarily utilized as a critical building block in the pharmaceutical and agrochemical industries, particularly for manufacturing antiviral agents, crop protection compounds, and advanced polymer intermediates. The key value proposition lies in its ability to introduce the cyclopropyl group into target molecules, enhancing metabolic stability and bioactivity. Strategically, it is indispensable for manufacturers seeking to develop next-generation therapeutics and high-performance crop solutions in a competitive, innovation-driven market.

2. Key Specifications & Technical Characteristics

• Chemical composition: Cyclopropylamine (C₃H₅NH₂); CAS No. 765-30-0

• Purity grade: ≥99.5% (GC assay) / Pharmaceutical & Technical grades available

• Physical characteristics: Colorless to light-yellow liquid; pungent amine odor

• Molecular weight: 57.09 g/mol

• Density: 0.824 g/mL at 25°C

• Boiling point: 49–50°C

• Flash point: –25°C (highly flammable)

• Packaging options: 1L, 25L, 200L UN-certified steel drums; 1,000L IBCs; custom bulk ISO tanks

• Shelf life: 24 months from date of manufacture when stored under nitrogen at 2–8°C in original sealed containers

3. Core Industrial Applications

• Pharmaceutical synthesis: Key intermediate for protease inhibitors (e.g., antiviral drugs for hepatitis C and HIV). Outperforms alternative amines due to its unique cyclopropyl ring, which reduces off-target metabolism and improves drug half-life.

• Agrochemical manufacturing: Used in the production of fungicides (e.g., cyproconazole) and insecticides. Provides superior environmental stability and targeted bioactivity compared to linear-chain amines.

• Polymer & specialty chemicals: Enables synthesis of cyclopropyl-containing polymers and fine chemicals, delivering higher thermal stability and rigidity than standard aliphatic amines.

• Cost advantage: Higher reaction yield and fewer purification steps vs. isopropylamine or other secondary amines in complex syntheses, reducing overall process costs by 15–20% in validated routes.

4. Competitive Advantages

• Quality consistency: ISO 9001:2025 certified production; each batch validated by GC-MS and titration with certificate of analysis (CoA) included.

• Supply reliability: Dual-sourced raw material strategy with 6-month buffer inventory; 99.5% on-time delivery rate across Asia, Europe, and North America.

• Logistics capability: DG-classified shipping (UN 2733) with real-time tracking; specialized temperature-controlled logistics partners.

• Price competitiveness: Tiered pricing model for contract volumes; transparent surcharge policy on raw material volatility.

• Sustainability: Process water recycling and solvent recovery systems reduce carbon footprint by 30% vs. industry average.

• Technical support: Dedicated application scientists for process optimization and regulatory documentation (MSDS, REACH, TSCA, Kosher upon request).

5. Commercial & Supply Information

• Minimum order quantity (MOQ): 100 kg for drum/IBC packaging

• BULK order quantity: 20 MT (20,000 kg) per shipment

• Loading capacity: 18–20 MT per 20-foot ISO tank container (depending on temperature and pressure specifications)

• Lead time: 14–21 days from PO confirmation for bulk orders; 5–7 days for packaged drums (ex-works)